Evaluation of GRADIOR, a cognitive rehabilitation application for dementia

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Early Stage Researcher (ESR15)

Angie Alejandra Diaz Baquero

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Prof. Manuel Franco

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Prof. María Victoria Perea

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Dr Henriette van der Roest

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Angie Alejandra is a psychologist graduated at the Catholic University of Colombia (UCC), during the course of her career, she has developed different research projects, including Neuropsychological evaluation of memory in patients with schizophrenia; was a young researcher belonging to Colciencias: Department administrative science, technology and innovation in agreement with the UCC, there, she developed a research project on Brain Electrical Activity of Attention in Adolescents Policonsumidores Using a BCI Instrument and a member of the seedbed of Neuropsychology the UCC. She completed her master’s degree in neuropsychology as a fellow at the University of Salamanca – Spain. Performing his master’s thesis on episodic memory in Traumatic Brain Injury (TBI).

She has worked as a neuropsychologist performing clinical neuropsychological evaluation and cognitive stimulation to patients with neurological pathologies, such as: Alzheimer’s, Parkinson’s, TCE, CVA, epilepsy.

Within INDUCT Alejandra is focusing on evaluation of cognitive rehabilitation program GRADIOR in people with dementia and MCI, which is also a topic of her PhD at University of Salamanca (Spain).

Start date September 2016
Duration 36 months


ESR15 develops a research project associated with the evaluation of the effectiveness of the use of new technologies such as the Gradior in cognitive rehabilitation in people with mild dementia and MCI through the implementation of a randomized clinical trial. ESR 15 will also translate, adapt and trial GRADIOR in the Netherlands. The GRADIOR software developed by the IDES is used in over 450 centres at national and international level within the social and health sector. It can remotely assess neuropsychology problems and allow the professional to tailor the interventions to the specific cognitive difficulties of the person with dementia. Within a rehabilitation program it is designed to train attention, perception, language, reasoning and memory. However, the effectiveness of GRADIOR has not been evaluated in depth.

Expected Results

The results will provide an evaluation of GRADIOR as an application suitable for remote evaluation and rehabilitation of cognitive problems. It will also (in collaboration with ESR9 and ESR10) provide a translation & second evaluation of GRADIOR providing evidence about how adaptable and transferable it is to other languages and settings.

Planned secondment(s)

Two secondments: 1) Participate in the development of the commission to be held at the University of Nottingham during the months of May and June 2019 with the aim of contributing to the adaptation of Gradior to the English population 2) Evaluate the integration of Gradior from a stay of at least two weeks at VU University – The Netherlands.



Vanova, M., Irazoki, E., García-Casal, J. A., Martínez-Abad, F., Botella, C., Shiells, K. R., & Franco-Martín, M. A. (2018). The effectiveness of ICT-based neurocognitive and psychosocial rehabilitation programmes in people with mild dementia and mild cognitive impairment using GRADIOR and ehcoBUTLER: study protocol for a randomised controlled trial. Trials19(1), 100.